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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecbf94724fe2148c56b58ad9ee2add45d35831637508fe3c5989f22f4e22b422' 
  AND token = 'nVkvYkWjDD1c6RMq5e+CgXl7KaX58c/21DyXpHEEHIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}