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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b0595f1fab13b6b484ee4c2b59af296b782b2b37de5139dfdb2c425c65da0fe' 
  AND token = 'O38edY9RnckmZo6uxL+QJTCpd3r5C3MMxDgun57IrAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}