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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67dbe2452fed94642b5ddb90f27f09e921bcc84221d27fe11141bdaa81eb9129' 
  AND token = 'NC1CupZ57+e+KLFSOj0Ow6O8/YAvVi/6jL2RzAJQ4DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}