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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f310d32d14265fdaf24cf44ec4971faf77cdd8f25f6d0d51324052ee85ddbd' 
  AND token = '/20B4+AbyjcBmTD72zhrVEPgQRclHzdEfSfzQivDV+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}