SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cda3fb2fd461065575daa26d7a144db12d6e8a077ccd23afba8a2bd85922325a' 
  AND token = '+N/atlKV53dsSEt/udlShQunVGsntR4dmPr+EV+lkRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}