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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b6450c602c08627d3591c0ea21a010c7dac4c24d0a88dab59525c8d8cc0a2c9' 
  AND token = 'o2UPkjo7xnP5qbIkLXIPcIcuHY1T0Lwdpucr1ZPwh/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}