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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96a1ab20096fe0d17b422e5da6378efd532c392724110653e17b65c2cfa3eed2' 
  AND token = 'XtV3QtcKERSJ5eFQksnsE/GAWWRpBvcq9U3iusE0FyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}