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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a35673724dc0c73485068343d29dbfe5e6c22c199ada6e299e721f1e6f6078e' 
  AND token = 'o+3s/79tJ+hNXx65qapnb4nd9RQzEKPyKcLlQ/b0h9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}