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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44ad569d1c0a27732fd1e04ccb6cdfea119f6d075a1cdd9e94cc8527531f5d10' 
  AND token = 'akrmjcJ2BVXE+CMJNgCnwk5pSDO+X11iCcpy3GaTvu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}