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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cfaf2594da34d098e3445cdcab47e4d23abc0305cb16d985669980a5e3bfd32' 
  AND token = 'MlG+R2x+8Ibd60PM7e9Y/MytHSdrcbTfpSZ49+G5Iss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}