SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b401a8ff559afbdc7cec8161dd220d89349de7991d2faa286eb3b2ff726c3dd' 
  AND token = 'xexnkVMRzrzLk6FHVc7dWBb5qYK7bu1P3zgliQJ1JTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}