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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e49a2c8fd6bcc0532187cf3fa5721646f95280c65cc6d440508bb9d35ce6028e' 
  AND token = 'OuOU3JzC8M77SG2/1paQjdNL3B7G6WDDJCIMkJTKgVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}