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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35aa2153cc780c5674168aa63b5ad9a013435251204fd2e2e82843c348d5f320' 
  AND token = '9oL6GWC7Kerg+LiyxpW1s3sY81xYK3KvQDBHlCpLGmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}