SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '793971ac80a9f164af9dd21dc8827eb499cb89931f97edd575fbdf51c0f050b3' 
  AND token = 'd1sAw16s4vrCkXj1kG/6E3WcoorzWpcCku0A27gfVSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}