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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06e25f5dad0d61f7004c16a81f07c676452d921b35a60e2ca1d5232c4e053a9c' 
  AND token = 'Atki68pyatEZA2UOW32EYg3lmHVdnpbyOUF5vv+YuJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}