SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f95abdb2e5c5f60a6470c2c3922994fc344d9593d35dc4ffeb829850bb3b74' 
  AND token = 'KHbzPEyQ4q2jAUS8m3m6Zle1t0e4pS7Vw71p2zqLzMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}