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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7c44c626ec9a1575ca7c952462f75aed5e8ea4412c06a1e4b521f20ad708120' 
  AND token = 'EgGIcHSsDVAhqNjIisEeEkKQSTZmlai5Q+VD5LghmwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}