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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cb5d3c9947e0329f0cef8843b5ee210bcd6fd423623f3f290fa1db463c41425' 
  AND token = '18AThQ/tClNQh1Mc9FK/xUW7gCiDHIT0aCQS36BNTLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}