SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0246d0c9df1075f28b0b0b09d50deee0d17de24e48cef579b9f5dd7055cb6855' 
  AND token = 'LPUIVIf2zCzvhFXOT1iutp5QzHILIrCfHPNKlWMpkos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}