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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '999f86591965c8820d9496654e59c4e40e6fef4ad03abac455520d4493586e48' 
  AND token = 'r6wlyPZ3EZfwlqI+4dos9/fU/M7aUihqsLEYhXbMn+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}