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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e59eb1706c043ea6db96fc16d6a877e1d5398b66e00ef7f1d17cafb0824dc4' 
  AND token = 'el9Pl+G6drAQAPhi4xTG3KJ+gvhomJgJ2DqF2FbBOs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}