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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0e8586c0cdf290c2a63945952a7def2f4ee09951ede4c47ba715a9ee3d91ed' 
  AND token = 'Yfzf18Pt9EsiU+AAuPTdDFq2mNsYw/VsUuwuIev9YMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}