SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd649187596072d11d1b418faef18ffc039305e0b5b4fa312623b5c278e980c2' 
  AND token = 'CWpHlXChv5mEIXOFlw/x4hCkNF6nEAirLBAB7hq43C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}