SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '229261c54a49cb5cdb1b5efb11bf6e9839b895f5ec6a0b17132a90fb7f2381b0' 
  AND token = 'jz4kZ3c0JBlOqpOGarX2zSot2RkYFF0Fo3d3kt2g67c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}