SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ef67b42dae2340cdcc1b73da6f2ea3b0a5edf9ac052e5724a246dd04e799cb5' 
  AND token = '86/M0ipQz0hllG5tICYuTfEaxrnqHSQHE7ZhvfcFgZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}