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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c48cc6bfc042d8c8540dc57f95a4a14be1812218c060870fd03ee9aa6f43784b' 
  AND token = 'qI/hUaDv436ZsOYxk++FRrq6Z4BtSdCIgyZe94UZagM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}