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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a00d4a88f3db692bce2c163c4c173e3c7c96a72c16111034b6f8900f085469' 
  AND token = 'jbFVxaDBe8qQpcmRGdNVwv+x0ZRNweflG+wwc8X//3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}