SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '256e04c2088bf25d75eadd6c8d73ee37ffb17e6433afcb3cf82487198d8fe278' 
  AND token = '9JgsnFve9uDUlnLupjMRMMw1/MdA9OsFDPyp9QCwRFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}