SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484fe4c7dfd91d6603dfd69d398280e068ebd8c2c58a4740a589304b718920ab' 
  AND token = 'rZnuiN+RnvOEP9x/9pyIRuwlnPjbUQXII6nqYWSgoKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}