SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b198bcef04c67ed7cd43349e894b8441fcb2f473d6fa1050dbc36bdc9523690' 
  AND token = '317oVI26dg47hap9R/kOapP7d3xSciwpgvbCBRcYeAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}