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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10fd18410c16e7b6c8cf296db6ab9e1ec1bb7d3a46d7376b3d1d90de364edea8' 
  AND token = 'E09zUE0FZHOwN6DVCIpoqsZDATUG6Iq3RRHHtFs550k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}