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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac09b279c46af994839df2fe04970e3ca0e1bfad0f011ed3e1eb6fac2f1ac53' 
  AND token = '7QPOan3LBtp7dL7WQC5Mv49AuWRMcGRuvw/SvMLIKtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}