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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8a3ad550c2dfbe3441315aca260c879ddeafb9aef704618414a500038c6f838' 
  AND token = '4rb3R67Oc1WX4isE1sGZ+C2LppgSW4BExc2xqaIKRgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}