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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4f50b63c8f5668073a4c869c21aefa1afa13d505c0aee1bbc35e777f94553d9' 
  AND token = 'TyfRQ23wJmp7xkkA440Jwx2bpS9ZPeQBbwATU31xc1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}