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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3809e81d2ad1d945367bd061700e174a3682dfba9b3fa5bb211376a314f88c70' 
  AND token = '2D0VfRfJ7eW4BD0MT17l4MXW7DlC/lLlQTV8/8Vj9x0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}