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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c67f3c161f7e748fa661b7ca5bf7591c1c1f68c82646fa83a4257d9448c9b0e' 
  AND token = 'rdCLr28HxTxgfV8DQVNhg8Rt+NC2aj8WQ3sxXDGjTWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}