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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2153bc63e68f60818c43d828914ddc0b5a33b75d15a570f7a41b9d72b5c9fa75' 
  AND token = 'h+kOhNaPWsT2Hos7Nuv65SPjq/CJX5A5MXT3/8PKsNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}