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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '252498c09e612d24e0e7a569af06b0ac8a57ae035c37176831c586c6a461e46c' 
  AND token = 'jEhRemag7H3ZxNiZbqaYsyopx1pp3tQrZBbQ7qH1/c4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}