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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '646ebf572a3d20a1103f4cc41f76a179c59487770c5441df0dbe1693d4daff1b' 
  AND token = 'DFO5GZp9Om1RCJX/5WyafLbwCfO7SdITMseFzqE8YBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}