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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b03b17e444fa95824305b117fdde0cbcaea71fa6a3e95312ad8257e5e755d7' 
  AND token = 'stJwB8/T/GDaHccDHX1x9bEnCs0QvgK0BOGym0+xzxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}