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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b1c16933cebbc644d92294e4780f0d7c5b44870e85e4912c3edb33e1f4ce3d2' 
  AND token = 'J8yd0yx9aY456t/WIwA8DypiYFJmZ1NlbT2yzZYtRvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}