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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51dc8038e4557b52bd3c175864d8335e6d7c0ceb9d6cc7209dfdacc79a5a6c78' 
  AND token = 'urVv1PcIV04PupgeWJI/AtWvmeMnsSC4pJ2ij7Eardo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}