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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e34a5252bef8fdd84bdf5a39209849e082b9469e48eed105fc7f76b3c6604c9' 
  AND token = 'FtFjwjbL7tw4N6D/fChb/k4mO8VtYHbYhlOAVJj3mvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}