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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '554804618de60927bb2256a5219698e596a0e387ef3766b0a8f0d68c15f95db4' 
  AND token = 'OyP1c19pMBpOSfRF1foZWCErMbbWfM+RZR/gliVwj3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}