SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77065c1fac7868e69592146ea481caa647f9fc2c27378eea2bcfb341274930db' 
  AND token = 'woXJQDvqV0nzyfEiaKcMXAsE2pz28pIJ+2JKU0/hvdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}