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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f186fc81f603806ae212d8a697b55bc683c4e311b8ebf2e7f05f058fb25fc05' 
  AND token = '+PqFG2HIEfK0KEc4yoXnL9pT/cnkOiSFfJ0yAnG6gQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}