SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddb803677a74d3e7f5eb3b026c16c0f32ac29079b976072257feb89e84a7f2cf' 
  AND token = '486yaVNeujPntUjsSg0axQuA5LH4caauHHV8NcTwCiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}