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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb09ae82afce2343f384103bee09860c993691f9154690d34160b55beb2142c' 
  AND token = 'J53xr8stKAvqo9uHvZdqTTfjRtTupuJtdQ15UOpFVKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}