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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6291d411a9687b6ae8c44fff17b4d8d1f15d8ccd342bcc5a734938ae329b1429' 
  AND token = 'rdR/x82f++dJ+KdyFcT4rovl/NrpQIf26FPUGUgt2cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}