SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0a9b1bbc8b9194024a76912a1df4bc0b195848fc408e5eef2aef29475c84a06' 
  AND token = 'l7WZyXg/9yUY8fEL8IYg438UvgA8En9sYwDe3s79jUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}